[Download] "Screening for Antiproliferative Activity of Six Southern Brazilian Species of Hypericum." by Phytomedicine: International Journal of Phytotherapy & Phytopharmacology # Book PDF Kindle ePub Free

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eBook details

• Title: Screening for Antiproliferative Activity of Six Southern Brazilian Species of Hypericum.
• Author : Phytomedicine: International Journal of Phytotherapy & Phytopharmacology
• Release Date : January 01, 2005
• Genre: Life Sciences,Books,Science & Nature,
• Pages : * pages
• Size : 190 KB

Description

Abstract The crude methanolic extracts of six species of Hypericum growing in southern Brazil (Hypericum caprifoliatum Cham. & Schlecht., H. carinatum Griseb., H. connatum Lam., H. myrianthum Cham. & Schlecht., H. polyanthemum Klotzsch ex Reichardt and H. ternum A. St. Hil.) were screened for their antiproliferative activity against two cell lines (HT-29 human colon carcinoma cells and H-460 non-small cell lung carcinoma). The most active crude extracts were those from H. caprifoliatum, H. myrianthum and, to a lesser extent, from H. connatum. All plants were submitted to fractionation with solvents in increasing polarity and re-assayed for the two cell lines used previously, as well as U-373 human malignant glioma cells. The most active fractions were the hexane fractions obtained from H. caprifoliatum, H. myrianthum and H. ternum.

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